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The Rational Clinical Examination
David L. Simel, Drummond Rennie
Alan N. Barkun, Steven A. Grover, Andrew Muir
Make the Diagnosis: Splenomegaly

Topics Discussed: criterion standard comparisons (diagnostic tests), dullness to percussion over traube's space, likelihood ratio, make the diagnosis, prior probability, splenomegaly

Excerpt: "During the general physical examination, patients should not be evaluated for splenomegaly.The prevalence of palpable splenomegaly in an otherwise healthy student population is low, approximating 3%8; 12% of normal postpartum women had palpable spleens.9 The prevalence of splenomegaly increases significantly among other selected populations, such as HIV patients (up to 66%10), or in areas in which schistosomiasis is prevalent.11..."
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